You can get the basics off the Amazon link above, but part of the fun was that I accidentally blew myself up with dynamite ("I regret nothing!"), before setting off waves of Indians to attack everyone. The game is double-printed in both English and Italian, so I insisted on pronouncing it "Dee-na-mee-tay." ("Must be Italian!")
Beer returns your hit points in this game. When Bro used a Beer card to regain a hit point, and then got shot by his wife and lost that hit point right back, Toly said "Well, you know, you only rent beer."
You do need a minimum of four players (we had 5 adults - note that the manufacturer's suggested age range is 8+ to 12+ depending on the basic and expansion packs). We ended with a near-stalemate at the end because we'd misread a rule, and yes, the rules are pretty complicated at first. Our copy is packaged in a neat giant bullet shape that at first everyone thought was just a nifty thermos.
Definitely worth playing again!